| Bioactivity | Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic activities[1][2]. | ||||||||||||
| Invitro | Hesperidin (5-200 µM; 24-72 h) induces potent cytotoxic effects in human osteosarcoma MG-63 cells[1].Hesperidin (5-150 µM; 48 h) induces early and late apoptosis in MG-63 cells[1].Hesperidin (10-30 µM) inhibits the activity of COX-2 and iNOS in a dose dependent manner in RAW 264.7 cells activated with LPS[2].Hesperidin (0.1 μg/mL; 2 h) decreases the formation of MDA and intracellular ROS, including chondrocyte apoptosis[3]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | Hesperidin | ||||||||||||
| CAS | 520-26-3 | ||||||||||||
| Formula | C28H34O15 | ||||||||||||
| Molar Mass | 610.56 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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