| Bioactivity | Heptaminol is a fatty amine with pressor properties and a potential antihypotension agent. Heptaminol is also a competitive inhibitor of norepinephrine uptake and an inhibitor of nicotine-induced catecholamine release (IC50: 650 μM). Heptaminol does not inhibit norepinephrine release induced by 59 mM K+ but rather inhibits high-affinity Na+-dependent norepinephrine uptake.[1][2]. |
| CAS | 372-66-7 |
| Formula | C8H19NO |
| Molar Mass | 145.24 |
| Appearance | 液体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Dib J, et al. Is heptaminol a (major) metabolite of octodrine? Drug Test Anal. 2019 Nov;11(11-12):1761-1763. [2]. Delicado EG, et al. Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells. Biochem Pharmacol. 1990 Aug 15;40(4):821-5. |