| Bioactivity | Heart-homing peptide is a peptide, CRPPR. CRPPR is a linear peptide containing arginine that has been identified as a heart-homing peptide owing to its ability to specifically bind to heart endothelium, and cysteine-rich protein-2 (CRIP-2) has been proposed as the receptor. Heart-homing peptide can be used for conjugating liposomes[1][2]. |
| CAS | 876460-72-9 |
| Sequence | Cys-Arg-Pro-Pro-Arg |
| Shortening | CRPPR |
| Formula | C25H45N11O6S |
| Molar Mass | 627.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Zhang H, et al. The cargo of CRPPR-conjugated liposomes crosses the intact murine cardiac endothelium. J Control Release. 2012 Oct 10;163(1):10-7. [2]. Rodríguez-Castejón J, et al. Targeting strategies with lipid vectors for nucleic acid supplementation therapy in Fabry disease: a systematic review. Drug Deliv Transl Res. 2024 Apr 8. |
Heart-homing peptide
CAS: 876460-72-9 F: C25H45N11O6S W: 627.76
Heart-homing peptide is a peptide, CRPPR. CRPPR is a linear peptide containing arginine that has been identified as a he
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