Bioactivity | Head activator neuropeptide is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. Head activator neuropeptide signals by binding GPR37 and stimulates cells to enter mitosis[1]. |
Invitro | Head activator neuropeptide (2 nM,0-60 分钟) 在转染了 GPR37-FLAG 的 COS-7 细胞中刺激 GPR37 的内化[1]。Head activator neuropeptide (EC50: 3.3 nM) 增加转染载脂蛋白和 GPR37[1] 的 CHO-K1 细胞中的 Ca2+ mobilisation[1]。Head activator neuropeptide (EC50: 5.6 nM) 刺激表达 GPR37 的青蛙卵母细胞的电流增加[1]。 |
Name | Head activator neuropeptide |
CAS | 79943-68-3 |
Shortening | Glp-PPGGSKVILF |
Formula | C54H84N12O14 |
Molar Mass | 1125.32 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |