Bioactivity | Harmane (Standard) is the analytical standard of Harmane. This product is intended for research and analytical applications. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC50=30 nM) over α2-adrenoceptor (IC50=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively). Harmane exhibits comutagenic effect. |
Name | Harmane (Standard) |
CAS | 486-84-0 |
Formula | C₁₂H₁₀N₂ |
Molar Mass | 182.22 |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |