| Bioactivity | Halofuginone (hydrochloride) (Standard) is the analytical standard of Halofuginone (hydrochloride). This product is intended for research and analytical applications. Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects[4]. |
| CAS | 1217623-74-9 |
| Formula | C16H18BrCl2N3O3 |
| Molar Mass | 451.14 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Halofuginone (hydrochloride) (Standard)
CAS: 1217623-74-9 F: C16H18BrCl2N3O3 W: 451.14
Halofuginone (hydrochloride) (Standard) is the analytical standard of Halofuginone (hydrochloride). This product is inte
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