| Bioactivity | Halofuginone (Standard) is the analytical standard of Halofuginone. This product is intended for research and analytical applications. Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects. |
| CAS | 55837-20-2 |
| Formula | C16H17BrClN3O3 |
| Molar Mass | 414.68 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Halofuginone (Standard)
CAS: 55837-20-2 F: C16H17BrClN3O3 W: 414.68
Halofuginone (Standard) is the analytical standard of Halofuginone. This product is intended for research and analytical
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This product is for research use only, not for human use. We do not sell to patients.