| Bioactivity | Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum.Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities[1][2]. |
| CAS | 2977255-36-8 |
| Formula | C11H17NO2 |
| Molar Mass | 195.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mohamed M M Abdel Razek, et al. A New Phenolic Alkaloid from Halocnemum strobilaceum Endophytes: Antimicrobial, Antioxidant and Biofilm Inhibitory Activities. Chem Biodivers. 2020 Oct;17(10):e2000496. [2]. Xiangru Zha, et al. Network pharmacology, molecular docking, and molecular dynamics simulation analysis reveal the molecular mechanism of halociline against gastric cancer. Mol Divers. 2024 Mar 19. |
Halociline
CAS: 2977255-36-8 F: C11H17NO2 W: 195.26
Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum.Halociline t
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