Bioactivity | Halichondrin B is found from the sponge Halichondria okadai. Halichondrin B is a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin (IC50 for tubulin polymerization of 1.2-1.4 μM). Halichondrin B shows anti-tumor activity[1]. |
Invitro | Halichondrin B (0.1-10 nM, 16 h) treatment inhibits the growth of L1210 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: |
Name | Halichondrin B |
CAS | 103614-76-2 |
Formula | C60H86O19 |
Molar Mass | 1111.31 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |