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Halichondrin B

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Bioactivity Halichondrin B is found from the sponge Halichondria okadai. Halichondrin B is a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin (IC50 for tubulin polymerization of 1.2-1.4 μM). Halichondrin B shows anti-tumor activity[1].
Invitro Halichondrin B (0.1-10 nM, 16 h) treatment inhibits the growth of L1210 cells[1]. Cell Cytotoxicity Assay[1] Cell Line:
Name Halichondrin B
CAS 103614-76-2
Formula C60H86O19
Molar Mass 1111.31
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.


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