| Bioactivity | HYOU1-IN-1 (Compound 33) is an inhibitor of hypoxia-upregulated protein 1 (HYOU1) with anti-inflammatory activity. HYOU1-IN-1 can be used in research on the regulation of fibroblast activation, chronic inflammation, and fibrotic diseases[1]. |
| Target | IC50: hypoxia-upregulated protein 1 (HYOU1). |
| CAS | 2832155-52-7 |
| Formula | C22H27Cl2N3O2 |
| Molar Mass | 436.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Papadopoulou D, et al. Discovery of the First-in-Class Inhibitors of Hypoxia Up-Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation. Angew Chem Int Ed Engl. 2024 Feb 10:e202319157. |
HYOU1-IN-1
CAS: 2832155-52-7 F: C22H27Cl2N3O2 W: 436.37
HYOU1-IN-1 (Compound 33) is an inhibitor of hypoxia-upregulated protein 1 (HYOU1) with anti-inflammatory activity. HYOU1
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