| Bioactivity | HX630 is a potent retinoic acid X receptor (RXR) agonist, can induce apoptosis, has anti-tumor effect, and can be used in Cushing's disease research[1]. |
| Invitro | HX630 (0.1-10 μM, 96 h) 可以剂量依赖性的抑制细胞增殖诱导 AtT20 细胞凋亡[1]。 Cell Viability Assay[1] Cell Line: |
| In Vivo | HX630（5 mg/kg，腹腔注射，每周 3 次，持续 3 周）在感染了AtT20 细胞的 BALB/c-nu 小鼠模型中，可以减少肿瘤的生长[1]。 Animal Model: |
| Name | HX630 |
| CAS | 188844-52-2 |
| Formula | C28H27NO2S |
| Molar Mass | 441.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Akiko Saito-Hakoda, et al. Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression. PLoS One. 2015 Dec 29;10(12):e0141960. |