| Bioactivity | HX1 is a potent reversible myeloperoxidase (MPO) inhibitor with an IC50 value of 50 nM. HX1 is bound within the active site cavity above the heme and blocks the substrate channel. HX1 is promising for research of inflammatory diseases[1]. |
| CAS | 1520083-61-7 |
| Formula | C14H10F6N4O3 |
| Molar Mass | 396.24 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Forbes LV, et al. Potent reversible inhibition of myeloperoxidase by aromatic hydroxamates. J Biol Chem. 2013 Dec 20;288(51):36636-47. |