| Bioactivity | HT-0712 is a Phosphodiesterase Type 4 (PDE4) inhibitor. HT-0712 enhances rehabilitation-dependent motor recovery and cortical reorganization after focal cortical ischemia[1][2]. |
| In Vivo | HT-0712 增强 CREB 依赖的基因表达，并改善携带CREB结合蛋白截断形式的小鼠（一种名为 Rubinstein-Taybi 综合征的智力障碍模型）的记忆缺陷。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| CAS | 617720-02-2 |
| Formula | C25H31NO3 |
| Molar Mass | 393.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Marco Peters, et al. The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice. Neuropsychopharmacology. 2014 Dec;39(13):2938-48. [2]. Erin MacDonald, et al. A novel phosphodiesterase type 4 inhibitor, HT-0712, enhances rehabilitation-dependent motor recovery and cortical reorganization after focal cortical ischemia. Neurorehabil Neural Repair. 2007 Nov-Dec;21(6):486-96. |