Bioactivity | Hsp90-in-35 (Compound 379) is an inhibitor of Hsp90. The IC50 of HSP90-IN-35 for Her2 is between 0.05 and 0.5 μM. HSP90-IN-35 has antitumor activity. HSP90-IN-35 can be used to synthesize PROTAC (HY-153881)[1]. |
CAS | 1207597-54-3 |
Formula | C27H33N5O5 |
Molar Mass | 507.58 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. DAVIS, et al. Preparation of substituted triazoles, particularly 4,5-diphenyl-4H-1,2,4-triazole-3-carboxamides, that modulate Hsp90 activity. WO2010017545 A2. |