| Bioactivity | HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows anti-influenza virus activity in MDCK cells, with EC50 values of 2.6, 3.9, and 17 μM for influenza A/H3N2, A/H1N1, and B, respectively[1]. |
| Invitro | HSP90-IN-14 (compound 4) (50 µM) inhibits influenza virus-induced cytopathic effect at non-toxic concentrations[1]. |
| Name | HSP90-IN-14 |
| CAS | 1995132-67-6 |
| Formula | C14H8Cl2N4O4S |
| Molar Mass | 399.21 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lamut A, et al. Anti-influenza virus activity of benzo[d]thiazoles that target heat shock protein 90. Bioorg Chem. 2020 May;98:103733. |
HSP90-IN-14
CAS: 1995132-67-6 F: C14H8Cl2N4O4S W: 399.21
HSP90-IN-14 (compound 4) is a potent Hsp90 (heat shock protein 90) inhibitor, with a Kd of 0.26 μM. HSP90-IN-14 shows a
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