| Bioactivity | HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1]. | ||||||||||||
| Target | IC50: 2 nM (Hormone sensitive lipase) | ||||||||||||
| Name | HSL-IN-1 | ||||||||||||
| CAS | 2095156-13-9 | ||||||||||||
| Formula | C19H13BClF3N2O4 | ||||||||||||
| Molar Mass | 436.58 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Ogiyama T, et al. Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation. Bioorg Med Chem. 2017 Apr 1;25(7):2234-2243. |
HSL-IN-1
CAS: 2095156-13-9 F: C19H13BClF3N2O4 W: 436.58
HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a signif
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