| Bioactivity | HSD17B13-IN-99 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of < 0.1 μM for estradiol. HSD17B13-IN-99 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1]. |
| Target | IC50: ≤ 0.1 μM (estradiol). |
| CAS | 2849338-46-9 |
| Formula | C24H19F3N4O4 |
| Molar Mass | 484.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. U.S., WO2022216626. 2022-10-13. |
HSD17B13-IN-99
CAS: 2849338-46-9 F: C24H19F3N4O4 W: 484.43
HSD17B13-IN-99 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of < 0
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