PeptideDB

HPP-9

CAS: F: C49H52N6O11 W: 900.97

HPP-9 is a Proteolysis-Targeting Chimeras (PROTACs) based on Hedgehog Pathway Inhibitor-1 (HPI-1), with the pIC50 of 6
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity HPP-9 is a Proteolysis-Targeting Chimeras (PROTACs) based on Hedgehog Pathway Inhibitor-1 (HPI-1), with the pIC50 of 6.71, that can degrade BET bromodomains. HPP-9 has antitumor activity[1[.
Name HPP-9
Formula C49H52N6O11
Molar Mass 900.97
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Meropi Bagka, et al. Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1. Nat Commun. 2023 Jul 1;14(1):3893.