Bioactivity | HPK1-IN-47 is a PROTAC HPK1 degrader (DC50: 23 nM in PBMCs). HPK1-IN-47 can be used for synthesis of PROTACs, such as PROTAC HPK1 Degrader-2 (HY-162544). HPK1-IN-47 can be used for research of HPK1-mediated diseases including cancer[1]. |
CAS | 2893885-42-0 |
Formula | C26H27N5O |
Molar Mass | 425.53 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sanjia XU, et al. PYRROLO [2, 3-b] PYRAZINE-BASED BIFUNCTIONAL COMPOUNDS AS HPK1 DEGRADERS AND THE USE THEREOF. Patent. WO2023006063. |