Bioactivity | HPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseases[1]. | ||||||||||||
Invitro | HPK1-IN-32 (Example A34, 0-2 μM, 2 h) 抑制 Jurkat 细胞内 pSLP76 活性,IC50 为 65 nM[1]。 | ||||||||||||
Name | HPK1-IN-32 | ||||||||||||
CAS | 2766481-17-6 | ||||||||||||
Formula | C28H37FN8O2 | ||||||||||||
Molar Mass | 536.64 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Sanjia XU, et al. 3-[(1h-pyrazol-4-yl)oxy]pyrazin-2-amine compounds as hpk1 inhibitor and use thereof. Patent. WO2022068848. |