Bioactivity | HPK1-IN-16 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-16 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2019051199A1, compound 39)[1]. |
Name | HPK1-IN-16 |
CAS | 2294965-95-8 |
Formula | C28H27FN4O |
Molar Mass | 454.54 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Oleg VECHORKIN, et al. 6-cyano-indazole compounds as hematopoietic progenitor kinase 1 (hpk1) modulators. Patent WO2019051199A1. |