| Bioactivity | HPK1-IN-15 is a potent and selective inhibitor of HPK1. Hematopoietic progenitor kinase 1 (HPKl) originally cloned from hematopoietic progenitor cells is a member of MAP kinase kinase kinase kinases (MAP4Ks) family. HPK1-IN-15 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer (extracted from patent WO2018049200A1, compound 50)[1]. |
| Name | HPK1-IN-15 |
| CAS | 2201098-03-3 |
| Formula | C24H21ClF3N5 |
| Molar Mass | 471.91 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hai-Fen Ye, et al. Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer. Patent WO2018049200A1. |