| Bioactivity | HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC50 of 9.9 nM[1]. |
| Target | IC50: 9.9 nM (H-PGDS) |
| Name | HPGDS inhibitor 2 |
| CAS | 2101626-26-8 |
| Formula | C20H24F2N2O3 |
| Molar Mass | 378.41 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| Reference | [1]. Deaton DN, et al. The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1456-1478. |
HPGDS inhibitor 2
CAS: 2101626-26-8 F: C20H24F2N2O3 W: 378.41
HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC5
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