| Bioactivity | HPA-IN-2 (Compound 2a-1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 8.2 μM and 450.7 μM against HPA and α-glucosidase, respectively[1]. |
| Target | IC50: 8.2 μM (HPA), 450.7 μM (α-glucosidase) |
| Invitro | HPA-IN-2 (Compound 2a-1) has four hydrogen bonds interacting with HPA[1]. |
| Name | HPA-IN-2 |
| CAS | 2885971-91-3 |
| Formula | C33H36N4O10 |
| Molar Mass | 648.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen W, et al. Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives. Bioorg Chem. 2022 Feb;119:105515. |
HPA-IN-2
CAS: 2885971-91-3 F: C33H36N4O10 W: 648.66
HPA-IN-2 (Compound 2a-1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 8.2
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This product is for research use only, not for human use. We do not sell to patients.