| Bioactivity | HPA-IN-1 (Compound 1) is a potent and selective human pancreatic α-amylase (HPA) inhibitor with IC50 values of 12.0 μM and 410.4 μM against HPA and α-glucosidase, respectively[1]. |
| Target | IC50: 12.0 μM (HPA), 410.4 μM (α-glucosidase) |
| Invitro | HPA-IN-1 (Compound 1) has three hydrogen bonds interacting with HPA[1]. |
| Name | HPA-IN-1 |
| Formula | C33H32N4O11 |
| Molar Mass | 660.63 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chen W, et al. Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives. Bioorg Chem. 2022 Feb;119:105515. |