| Bioactivity | HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. HMG-CoA Reductase-IN-1has high HMGR inhibitory activity and OATP1B1 affinity with pIC50 and pKm values of 8.54 and 1.98, respectively. HMG-CoA Reductase-IN-1 can be used for the research of hypercholesterolemia[1]. |
| Target | pIC50: 8.54 (HMGR); pKm: 1.98 (OATP1B1) |
| Name | HMG-CoA Reductase-IN-1 |
| Formula | C27H29N3O7 |
| Molar Mass | 507.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Samizo S, et al. Predictive Modeling of HMG-CoA Reductase Inhibitory Activity and Design of New HMG-CoA Reductase Inhibitors. ACS Omega. 2023 Jul 18;8(30):27247-27255. |
HMG-CoA Reductase-IN-1
CAS: F: C27H29N3O7 W: 507.54
HMG-CoA Reductase-IN-1 is a HMG-CoA reductase inhibitor. HMG-CoA Reductase-IN-1has high HMGR inhibitory activity and OAT
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.