| Bioactivity | HMB-Val-Ser-Leu-VE is a prototype vinyl ester inhibitor. HMB-Val-Ser-Leu-VE is against trypsin-like (T-L) proteasome activity with an IC50 of 0.033 μM[1]. |
| Target | IC50: prototype vinyl ester |
| Name | HMB-Val-Ser-Leu-VE |
| CAS | 862891-04-1 |
| Sequence | {HMB}-Val-Ser-Leu-{VE} |
| Shortening | {HMB}-VSL-{VE} |
| Formula | C26H39N3O7 |
| Molar Mass | 505.60 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Anna Baldisserotto, et al. C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors. Eur J Med Chem. 2008 Jul;43(7):1403-11. |
HMB-Val-Ser-Leu-VE
CAS: 862891-04-1 F: C26H39N3O7 W: 505.60
HMB-Val-Ser-Leu-VE is a prototype vinyl ester inhibitor. HMB-Val-Ser-Leu-VE is against trypsin-like (T-L) proteasome act
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