Bioactivity | HLE-IN-1 (Compound 4) is a human leukocyte elastase HLE inhibitor (Ki=1.8 nM). HLE-IN-1 is used in emphysema and inflammamry pulmonary research[1]. |
CAS | 13947-21-2 |
Formula | C8H6ClNO3S |
Molar Mass | 231.66 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hlasta, et al. A benzisothiazolone class of potent, selective mechanism-based inhibitors of human leukocyte elastase. Bioorganic & Medicinal Chemistry Letters, 4(15), 1801–1806. |