| Bioactivity | HIV-1 protease-IN-14 (compound 5ae) is a potent HIV-1 protease inhibitor with Ki values of 0.28, 56.9 nM for WT HIV-1 PR, R41T HIV-1 PR, respectively. HIV-1 protease-IN-14 shows low cytotoxicity[1]. |
| Target | Ki: 0.28 nM (WT HIV-1 PR); 56.9 nM (R41T HIV-1 PR) |
| Formula | C30H42N2O8S |
| Molar Mass | 590.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ur Rehman MA, et al. Design, Synthesis, and Biological Evaluation of Darunavir Analogs as HIV-1 Protease Inhibitors. ACS Bio Med Chem Au. 2024 Sep 19;4(5):242-256. |
HIV-1 protease-IN-14
CAS: F: C30H42N2O8S W: 590.73
HIV-1 protease-IN-14 (compound 5ae) is a potent HIV-1 protease inhibitor with Ki values of 0.28, 56.9 nM for WT HIV-1 PR
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