Bioactivity | HIV-1 inhibitor-65 (compound 3c) is an inhibitor of HIV-1 (EC50: 2.9 nM) and an activator of protein kinase C (PKC). HIV-1 inhibitor-65 inhibits syncytium formation (EC50: 7.0 nM) and inhibits HIV-1 entry and HIV-1 reverse transcriptase[1]. |
Target | EC50: 2.9 nM (HIV-1) |
Formula | C40H53FO6 |
Molar Mass | 648.84 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Huang X, et al. Synthesis and anti-HIV activities of phorbol derivatives. Chin J Nat Med. 2024 Feb;22(2):146-160. |