| Bioactivity | HIV-1 inhibitor-53 is a dual HIV-1 protease and reverse transcriptase inhibitor. HIV-1 inhibitor-53 inhibits HIV-1 protease (PR) and reverse transcriptase (RT) activity with IC50 values of 1.93 nM and 2.35 μM, respectively. HIV-1 inhibitor-53 can be used for the research of acquired immune deficiency syndrome (AIDS)[1]. |
| Target | IC50: 1.93 nM (protease); 2.35 μM (reverse transcriptase) |
| Invitro | HIV-1 inhibitor-53 对 HIV-1 蛋白酶 (PR) 和逆转录酶 (RT) 具有抑制作用,IC50 值分别为 1.93 nM 和 2.35 μM[1]。 |
| Name | HIV-1 inhibitor-53 |
| Formula | C30H34N2O8S |
| Molar Mass | 582.66 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mei Zhu, Structure based design and evaluation of benzoheterocycle derivatives as potential dual HIV-1 protease and reverse transcriptase inhibitors. Eur J Med Chem |