Bioactivity | HIV-1 inhibitor-26 (compound 9a) is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 value of 1.4 μM. HIV-1 inhibitor-26 has low cytotoxicity with a CC50 of 1486 μM in PBMCs. HIV-1 inhibitor-26 can be used for researching AIDS[1]. |
Target | IC50: 1.4 μM (HIV-1 RT) |
Name | HIV-1 inhibitor-26 |
CAS | 2415504-88-8 |
Formula | C43H33ClN2O9 |
Molar Mass | 757.18 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Forezi LDSM, et al. Design, synthesis, in vitro and in silico studies of novel 4-oxoquinoline ribonucleoside derivatives as HIV-1 reverse transcriptase inhibitors. Eur J Med Chem. 2020;194:112255. |