HIV-1 capsid inhibitor 1_product_DataBase

Bioactivity	HIV-1 capsid inhibitor 1 is a potent HIV-1 Capsid inhibitor with an EC50 value of 3.13 µM. HIV-1 capsid inhibitor 1 shows antiviral activities[1].
Invitro	HIV-1 capsid inhibitor 1 (compound 6a-9) 在 TZM-bl 细胞中表现出抗 HIV 活性，EC50 值为 3.13 µM，CC50 值为 >16.48 µM[1]。HIV-1 capsid inhibitor 1 在 HIV-1 NL4-3 生命周期的早期和晚期显示出抗病毒活性，IC50 分别为 8.18、0.32 µM<[1]。HIV-1 capsid inhibitor 1 在人肝微粒体和血浆中表现出代谢稳定性[1]。
Name	HIV-1 capsid inhibitor 1
CAS	2396382-78-6
Formula	C34H31FN6O4
Molar Mass	606.65
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Sun L, et al. Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities. Eur J Med Chem. 2020 Mar 15;190:112085.

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