HIF-2α-IN-9_product_DataBase

CAS: 2648334-36-3 F: C12H13F5O4S2 W: 380.35

HIF-2α-IN-9 (compound 35r) is an inhibitor ofHIF-2α. HIF-2α-IN-9 inhibits VEGF-A (IC50=305 nM), and regulates growth-

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	HIF-2α-IN-9 (compound 35r) is an inhibitor ofHIF-2α. HIF-2α-IN-9 inhibits VEGF-A (IC50=305 nM), and regulates growth-promoting genes in tumor cells, reactivates macrophage-mediated tumor immunity[1].
Target	HIF-2α
Name	HIF-2α-IN-9
CAS	2648334-36-3
Formula	C12H13F5O4S2
Molar Mass	380.35
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Buchstaller H P, et al. Discovery of Cycloalkyl [c] thiophenes as Novel Scaffolds for Hypoxia-Inducible Factor-2伪 Inhibitors[J]. Journal of Medicinal Chemistry, 2023..

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