| Bioactivity | HH0043 (Compound 10f) is an orally active and potent SOS1 inhibitor, with IC50 value of 5.8 nM. HH0043 can be used for the research of cancer[1]. |
| CAS | 2922069-42-7 |
| Formula | C23H24F3N5O |
| Molar Mass | 443.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Li D, et al. Lead Identification of Novel Naphthyridine Derivatives as Potent SOS1 Inhibitors. ACS Med Chem Lett. 2024 Jun 3;15(6):958-964. |