Bioactivity | HDP 30.1699, the derivative of α-Amanitin,shows considerable cross-links. The cysteine residues of the anti-HER2 THIOMAB antibody are used for conjugation of the cysteine reactive linker–Amanitin compound, HDP 30.1699, with a cleavable linker by maleimide chemistry[1][2]. |
Name | HDP 30.1699 |
CAS | 2004724-36-9 |
Formula | C61H80N14O19S |
Molar Mass | 1345.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Torsten HECHLER, et al. Amanitin antibody conjugates. WO2018115466A1. |