| Bioactivity | HDAC8-IN-8 (15a) is an HDAC8 inhibitor, with IC50 values of 23.9 μM and 268.2 μM for hHDAC8 and smHDAC8 respectively. And for hHDAC1 and hHDAC6, the IC50 values are 12.1 μM and 2.9 μM respectively. HDAC8-IN-8 can be used in schistosomiasis-related research[1]. |
| Invitro | HDAC8-IN-8 (15a) (50 μM，24 h) 作用下 HEK293 细胞活力为 69.1%[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> HDAC8-IN-8 相关抗体: |
| CAS | 1884231-52-0 |
| Formula | C15H15NO4 |
| Molar Mass | 273.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Heimburg T, et al. Structure-Based Design and Synthesis of Novel Inhibitors Targeting HDAC8 from Schistosoma mansoni for the Treatment of Schistosomiasis. J Med Chem. 2016 Mar 24;59(6):2423-35. |