PeptideDB

HDAC6 degrader-4

CAS: 2235382-05-3 F: C37H45N9O10 W: 775.81

HDAC6 degrader-4 is a PROTAC and a selective HDAC6 degrader consists of a non-selective HDAC inhibitor and thalidomide-t
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Bioactivity HDAC6 degrader-4 is a PROTAC and a selective HDAC6 degrader consists of a non-selective HDAC inhibitor and thalidomide-type E3 ligase ligand. HDAC6 degrader-4 can be used for cancer research[1].
Invitro HDAC6 degrader-4 (0.04-10 μM, 12 h) 剂量依赖性地抑制 MCF-7 细胞中的 HDAC6[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> HDAC6 degrader-4 相关抗体:
CAS 2235382-05-3
Formula C37H45N9O10
Molar Mass 775.81
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Yang K, et al. Development of the first small molecule histone deacetylase 6 (HDAC6) degraders. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2493-2497.