| Bioactivity | HDAC6 degrader-1 is a PROTAC that comprises a selective HDAC6 inhibitor Nexturastat A (Nex A) as the HDAC6 binder, a linker and a ligand for recruiting E3 ligase. HDAC6 degrader-1 induces significant degradation of HDAC6, exhibits excellent selectivity against other HDACs, and demonstrates efficient inhibition of cell proliferation[1]. |
| Name | HDAC6 degrader-1 |
| CAS | 2439058-23-6 |
| Formula | C40H45N9O9 |
| Molar Mass | 795.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. An Z, et al. Developing potent PROTACs tools for selective degradation of HDAC6 protein [published correction appears in Protein Cell. 2019 Feb 22;:]. Protein Cell. 2019;10(8):606-609. |
HDAC6 degrader-1
CAS: 2439058-23-6 F: C40H45N9O9 W: 795.84
HDAC6 degrader-1 is a PROTAC that comprises a selective HDAC6 inhibitor Nexturastat A (Nex A) as the HDAC6 binder, a lin
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