| Bioactivity | HDAC-IN-58 is a HDAC inhibitor. HDAC-IN-58 has HDAC6-specific inhibition activity with an IC50 value of 2.06 nM. HDAC-IN-58 can be used for the research of chronic diseases, including neurodegenerative and psychiatric conditions[1]. |
| Target | IC50: 2.06 nM (HDAC6) |
| Name | HDAC-IN-58 |
| CAS | 2071224-39-8 |
| Formula | C16H13ClF2N4O3S |
| Molar Mass | 414.81 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Motlová L, et al. Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6). ACS Chem Biol. 2023 Jul 21;18(7):1594-1610. |
HDAC-IN-58
CAS: 2071224-39-8 F: C16H13ClF2N4O3S W: 414.81
HDAC-IN-58 is a HDAC inhibitor. HDAC-IN-58 has HDAC6-specific inhibition activity with an IC50 value of 2.06 nM. HDAC-IN
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