| Bioactivity | HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with EC50 of 0.134 and 0.027 μM. HCV-IN-45 inhibits 1a/2a and 1b/2a cell culture-adapted HCV (HCVcc), with EC50 of 0.024 and 0.012μM. HCV-IN-45 inhibits the entry of the virus into hepatocyte, and blocks the cell-cell spread[1]. |
| CAS | 301211-35-8 |
| Formula | C16H19F3N6O3 |
| Molar Mass | 400.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Baldick CJ, et al., A novel small molecule inhibitor of hepatitis C virus entry. PLoS Pathog. 2010 Sep 2;6(9):e1001086. |
HCV-IN-45
CAS: 301211-35-8 F: C16H19F3N6O3 W: 400.36
HCV-IN-45 (Compound EI-1) is an inhibitor for hepatitis C virus (HCV), that inhibits 1a and 1b HCV pseudoparticles with
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