| Bioactivity | HBV-IN-48 is an HBV inhibitor. HBV-IN-48 has antiviral activity against HBV in HepDE19 cells, with an EC50 value of 0.005 μM. HBV-IN-48 can reduce serum HBV DNA levels in mouse models of HBV infection[1]. |
| CAS | 2743466-04-6 |
| Formula | C22H15F4N3O3 |
| Molar Mass | 445.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Mesaros E F, et al. Conformationally Constrained Isoquinolinones as Orally Efficacious Hepatitis B Capsid Assembly Modulators[J]. ACS Medicinal Chemistry Letters, 2024. |