| Bioactivity | HBV-IN-47 (compound 4a) is a capsid assembly regulator with inhibitory activity against hepatitis B virus (HBV). HBV-IN-47 exhibits strong anti-HBV activity in HepAD38 cells with low toxicity (EC50=0.24 μM). HBV-IN-47 can be used for the study of chronic hepatitis B (CHB)[1]. |
| Formula | C20H19F3N2O5S |
| Molar Mass | 456.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. M Liang, et al. "Design, synthesis and anti-HBV activity study of novel HBV capsid assembly modulators." Bioorganic & Medicinal Chemistry Letters (2024): 129913. |