| Bioactivity | HBV-IN-24 (compound (2ʹS, 6S)-1a) is a potent HBV inhibitor. HBV-IN-24 exhibits potent inhibition activity against HBV DNA, HBsAg, and HBeAg, with EC50 values of 0.6, 0.6, and 4.6 nM, respectively. HBV-IN-24 shows excellent antiviral activity, could have improved neurotoxicity[1]. |
| Target | EC50: 0.6 nM (HBV DNA), 0.6 nM (HBsAg), and 4.6 nM (HBeAg) |
| Name | HBV-IN-24 |
| Formula | C23H27NO6 |
| Molar Mass | 413.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Qin X, et al. Identification of dihydroquinolizinone derivatives with cyclic ether moieties as new anti-HBV agents. Eur J Med Chem. 2022 Aug 5;238:114518. |