| Bioactivity | HB-3-20 leads to degradation of the cell surface integrin αVβ5. Transglutaminase 2 (TG2) has specificity for HB-3-20 (kcat/KM=0.16 μM-1min-1)[1]. |
| Sequence | Ac-Pro-Gln-Leu-Pro-Phe-Gly-Gly-Gly-Gly-Ser-Arg-Gly-Asp-Val-Phe-NH2 |
| Shortening | Ac-PQLPFGGGGSRGDVF-NH2 |
| Formula | C69H102N20O20 |
| Molar Mass | 1531.67 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Elise Loppinet, et al. Targeted Lysosomal Degradation of Secreted and Cell Surface Proteins through the LRP-1 Pathway. J Am Chem Soc. 2023 Aug 30;145(34):18705-18710. |