| Bioactivity | HAEGT is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide, and the sequence is His-Ala-Glu-Gly-Thr. HAEGT acts as a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV) 1, in which the N-terminal His-Ala is catalyzed cleavage by DPP-IV. HAEGT can be used in the research of diabetes, obesity[1]. | ||||||
| Invitro | HAEGT (0-500 μM) is a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV)[1].HAEGT can be catalyzed cleavage by DPP-IV with a km value of 38 μM, Kcat value of 3.1 S-1[1]. | ||||||
| Name | HAEGT | ||||||
| CAS | 852155-81-8 | ||||||
| Sequence | His-Ala-Glu-Gly-Thr | ||||||
| Shortening | HAEGT | ||||||
| Formula | C20H31N7O9 | ||||||
| Molar Mass | 513.50 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |