Bioactivity | H3K27(Me) (15-34), a histone peptide, is a repressive chromatin markderived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me)[1][2]. |
Name | H3K27(Me) (15-34) |
Sequence | Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-Ala-Arg-{Lys(Me)}-Ser-Ala-Pro-Ala-Thr-Gly-Gly |
Shortening | APRKQLATKAAR-{Lys(Me)}-SAPATGG |
Formula | C85H152N30O25 |
Molar Mass | 1994.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Elizabeth T Wiles, et al. H3K27 Methylation: A Promiscuous Repressive Chromatin Mark. Curr Opin Genet Dev. 2017 Apr;43:31-37. [2]. Brian P Chadwick, et al. Multiple Spatially Distinct Types of Facultative Heterochromatin on the Human Inactive X Chromosome. Proc Natl Acad Sci U S A. 2004 Dec 14;101(50):17450-5. |