| Bioactivity | H2-003 is a selective human DGAT2 inhibitor that inhibits triglyceride (TG) biosynthesis. H2-003 also effectively inhibits lipid droplet formation in 3T3-L1 cells. H2-003 can be used for research on DGAT2 and TG-related metabolic diseases[1]. |
| Target | DGAT2. |
| Name | H2-003 |
| CAS | 1060438-30-3 |
| Formula | C25H26N4O4 |
| Molar Mass | 446.50 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kim MO, et al. Discovery of a novel class of diacylglycerol acyltransferase 2 inhibitors with a 1H-pyrrolo[2,3-b]pyridine core. Biol Pharm Bull. 2014;37(10):1655-60. |