| Bioactivity | H117 is a PROTAC target protein ligand that can be used to synthesize PROTAC HP211206 (HY-170598). H117 has competitive binding and inhibition ability on SARS-CoV-2 main protease (Mpro) with an IC50 of 151.3 nM[1]. |
| Target | IC50: 151.3 nM (SARS-CoV-2 Mpro) |
| Formula | C24H37F2N5O6 |
| Molar Mass | 529.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sang X, et al. A Chemical Strategy for the Degradation of the Main Protease of SARS-CoV-2 in Cells. J Am Chem Soc. 2023 Dec 20;145(50):27248-27253. |