PeptideDB

H-Ile-Lys-Val-Ala-Val-OH

CAS: 131167-89-0 F: C25H48N6O6 W: 528.69

H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adh
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Bioactivity H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways[1][2].
Invitro H-Ile-Lys-Val-Ala-Val-OH (0-2.5 mM, 0-48 h) 诱导骨髓间充质干细胞(BMMSC)增殖和增殖细胞核抗原(PCNA)合成[2]。H-Ile-Lys-Val-Ala-Val-OH (5 mM, 24 h) 诱导 BMMSC 细胞周期,使细胞从 G0/G1 进入 S 期并阻止它们进入 G2/M 期[2]。H-Ile-Lys-Val-Ala-Val-OH (0-2.5 mM, 0-48 h) 通过增强 BMMSCs 中 ERK1/2 和 Akt 的磷酸化水平激活 MAPK/ERK 和 PI3K/Akt 信号通路[2]。 Cell Proliferation Assay[2] Cell Line:
Name H-Ile-Lys-Val-Ala-Val-OH
CAS 131167-89-0
Sequence H-Ile-Lys-Val-Ala-Val-OH
Shortening IKVAV
Formula C25H48N6O6
Molar Mass 528.69
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.